By M. Bergener (auth.), Professor Dr. med. Manfred Bergener, Professor Barry Reisberg M. D. (eds.)
Senile dementia is among the significant illnesses confronting mankind during this century. to some degree the matter has, after all, consistently existed. The was once sufficiently troubling to classical philosophers and jurists to have it sounds as if provoked reviews through Solon in nearly 500 B. C. and Plato within the fourth century B. C. (Plutarch 1967 translation; Plato 1921 translation). scientific attractiveness should be traced at the very least way back to the second one century A. D. (Adams 1861). notwithstanding, a number of components have converged during this century to increase absolutely the dimensions of the matter of senile dementia and to extend societal, clinical, and medical recogni tion of the importance of the situation. maybe an important issue with regards to the current value of senile dementia is demographic. even though the human inhabitants has been expanding because the mid-eighteenth century, it has in simple terms been because the introduction of the 20 th century reduce in mortality has been famous for these over the age of forty five (McKeown 1976). as a result, absolutely the variety of elderly people and the share of more and more elderly folks within the populations of the world's commercial international locations were gradually expanding. for instance, within the usa, four% ofthe inhabitants used to be over the age of sixty five in 1900. within the 1970 census, this percentage had grown to 10%.
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Senile dementia is likely one of the significant illnesses confronting mankind during this century. to a point the matter has, after all, constantly existed. The situation was once sufficiently troubling to classical philosophers and jurists to have it sounds as if provoked reviews via Solon in nearly 500 B. C. and Plato within the fourth century B.
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Extra info for Diagnosis and Treatment of Senile Dementia
In the Kawasaki study, almost all the aged with dementia had physical illnesses, hypertension and cerebrovascular disorder being the most frequent. Although some investigators (Schoenberg et al. 1985; Sulkavaet a1. 1983; Peck et al. 1973) found that most deaths in people with dementia were due to respiratory or cardiovascular disease, in the aged with dementia there is an interaction with other conditions predisposing to early death such as bedridden incontinence and physical illness. The behavioral disturbance in the demented elderly including institutionalization, responsible for a significant amount of family stress and burden.
1] utilizing cultured skin fibroblasts from OAT patients emphasizes this point. All OAT cells, in appropriate in vitro conditions, stained for paired helical filaments whereas none of the control cells manifested this property . These findings support the hypothesis that OAT may be a systemic illness and provide the basis for a diagnostically important test [1, 3]. Bergener. ) Diagnosis and Treatment of Senile Dementia © Springer· Verlag Berlin Heidelberg 1989 18 C. A. Shamoian Should these findings be rephcated, a critical laboratory test would be available to confirm a clinical diagnosis of DAT which, even to the present day, in the early stages of the illness is difficult to make with any degree of accuracy and confidence.
Geriatrics 41: 30-46 15. Rossor MN, Iversen LL, Reynolds GP, Mountjoy CO; et al. (1984) Neurochemical characteristics of early and late onset types of Alzheimer's disease. Br Med 1 288: 961-964 16. St George-Hyslop PH, Tanzi RE, Polinsky RJ et al. (1987) The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 235: 885-890 17. Selkoe Dl, Bell DS, Podlisny MB (1987) Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 235: 873-877 18.
Diagnosis and Treatment of Senile Dementia by M. Bergener (auth.), Professor Dr. med. Manfred Bergener, Professor Barry Reisberg M. D. (eds.)