Read e-book online Current Cancer Treatment – Novel Beyond Conventional PDF

By Öner Özdemir

ISBN-10: 9533073977

ISBN-13: 9789533073972

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J. (2005). Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity. Cancer Research, Vol. 65, (August 2005), pp. H. D. (2010) Phase-I clinical trial of IL-12 plasmid/lipopolymer complexes for the treatment of recurrent ovarian cancer. Gene Therapy, Vol. 3, (March 2010), pp. L. A. (2006). Intraperitoneal cisplatin and paclitaxel in ovarian cancer. The New England Journal of Medicine, Vol. 354, No. 1, (January 2006), pp.

Cancer Control, Vol. 18, No. 1, (January 2011), pp. ; Stein, S. & Cameron, D. (2006). Lapatinib plus capecitabine for HER2-positive advanced breast cancer. The New England Jornal of Medicine, Vol. 355, No. 26, (December 2006), pp. ; Nitz, U. & Harbeck, N. (2009). Triplenegative breast cancer--current status and future directions. Annals of Oncology, Vol. 20, No. 12, (December 2009), pp. M. F. (2004). CA125- and tumor-specifc T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients.

Among these, two nanodrugs are indicated by FDA for the treatment of OVCA and/or BC. Abraxane® (Abraxis Bioscience) is a paclitaxel albumin-bound injectable particle suspension approved by FDA in 2005 for the treatment of metastatic BC which failed to respond to combined chemotherapy or that relapse within 6 moths of adjuvant chemotherapy. This is a novel solvent-free formulation of paclitaxel in which it is bound to albumin forming 130 nm stable particles. The classical solvent to paclitaxel, Cremophor-EL, causes severe hypersensitivity reaction, thus this new formulation eliminates solvent-related toxicity.

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Current Cancer Treatment – Novel Beyond Conventional Approaches by Öner Özdemir


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