By I. Chaikovsky, N. Sydorova
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Molecular biology and genetics will help us with information no less important. Therefore, we need many more research groups than in the past century and in the clinical area, multidisciplinary cooperation. Maybe this is the biggest challenge for the 21st century. 6. References Arens, R. & Marcus, C. L. (2004). Pathophysiology of upper airway obstruction: a developmental perspective. Sleep, 27, 997-1019. ISSN 0161-8105 Bradley, T. D. & Floras, J. S. (2009). Obstructive sleep apnoea and its cardiovascular consequences.
It is a progressive chronic disease process with contributions from environment, lifestyle and genetic factors. , 1994) and we know that its susceptibility can be mediated by both genetic and environmental factors (Talmud, 2007). The influence of a family history of CHD, particularly of early onset, while universally recognized as important, has proved difficult to clarify fully. Habits and behaviors tend to persist in families, and familial aspects of the disease are partially explained by associations of behavioral risk factors and others in which behavior is important, including obesity, smoking, hypertension, dyslipidemia and diabetes.
2009). Obstructive sleep apnoea and its cardiovascular consequences. Lancet, 373, 82-93. , Khair, O. & Lip, G. Y. H. (2010). Obstructive sleep apnea and cardiovascular disease. International Journal of Cardiology, 139, 7-16. ISSN 0167-5273 Cairo, G. & Pietrangelo, A. (2000). Iron regulatory proteins in pathobiology. Biochemical Journal, 352, 241-250. ISSN 0264-6021 Chisolm, G. M. & Steinberg, D. (2000). The oxidative modification hypothesis of atherogenesis: An overview. Free Radical Biology and Medicine, 28, 1815-1826.
Coronary Artery Diseases by I. Chaikovsky, N. Sydorova