Read e-book online Contribution of AZAP Type Arf, GAPsto Cancer Cell Migration, PDF

By George F. Vande Woude and George Klein (Eds.)

ISBN-10: 0123743591

ISBN-13: 9780123743596

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And Beachy, P. A. (2000). Genetics of ventral forebrain development and holoprosencephaly. Curr. Opin. Genet. Dev. 10, 262–269. , Luoh, S. , and de Sauvage, F. J. (2000). Gli regulation by the opposing activities of fused and suppressor of fused. Nat. Cell Biol. 2, 310–312. , and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795–801. Ogden, S. , Stegman, M. , and Robbins, D. J. (2004). Regulation of Hedgehog signaling: A complex story. Biochem.

2004). Isolation of development and differentiation enhancing factor‐like 1 (DDEFL1) as a drug target for hepatocellular carcinomas. Int. J. Oncol. 24, 43–48. , Holt, M. , and Cockcroft, S. (2002). Continual production of phosphatidic acid by phospholipase D is essential for antigen‐stimulated membrane ruffling in cultured mast cells. Mol. Biol. Cell 13, 3730–3746. , and Sabe, H. (2005). Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. EMBO J.

III. IV. V. VI. Introduction The Functions of Drosophila Sufu: Lessons Learned from the Wing Imaginal Disc The Conserved and Distinct Roles of Mammalian Sufu in Sonic Hh Signaling Regulation of Sufu Activity Sufu as a Tumor Suppressor Concluding Remark References Originally identified as factors affecting Drosophila embryogenesis, the Hedgehog (Hh) pathway is one of the primary signaling systems that specify patterns of cell growth and differentiation during vertebrate development. Mutations in various components of this pathway frequently occur in tumors originated from the skin, cerebellum, and skeletal muscle, and abnormal pathway activity is associated with a subset of lung, digestive tract, pancreatic, and prostate cancers.

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Contribution of AZAP Type Arf, GAPsto Cancer Cell Migration, and Invasion by George F. Vande Woude and George Klein (Eds.)

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