By George F. Vande Woude and George Klein (Eds.)
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Additional resources for Contribution of AZAP Type Arf, GAPsto Cancer Cell Migration, and Invasion
And Beachy, P. A. (2000). Genetics of ventral forebrain development and holoprosencephaly. Curr. Opin. Genet. Dev. 10, 262–269. , Luoh, S. , and de Sauvage, F. J. (2000). Gli regulation by the opposing activities of fused and suppressor of fused. Nat. Cell Biol. 2, 310–312. , and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795–801. Ogden, S. , Stegman, M. , and Robbins, D. J. (2004). Regulation of Hedgehog signaling: A complex story. Biochem.
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III. IV. V. VI. Introduction The Functions of Drosophila Sufu: Lessons Learned from the Wing Imaginal Disc The Conserved and Distinct Roles of Mammalian Sufu in Sonic Hh Signaling Regulation of Sufu Activity Sufu as a Tumor Suppressor Concluding Remark References Originally identified as factors affecting Drosophila embryogenesis, the Hedgehog (Hh) pathway is one of the primary signaling systems that specify patterns of cell growth and differentiation during vertebrate development. Mutations in various components of this pathway frequently occur in tumors originated from the skin, cerebellum, and skeletal muscle, and abnormal pathway activity is associated with a subset of lung, digestive tract, pancreatic, and prostate cancers.
Contribution of AZAP Type Arf, GAPsto Cancer Cell Migration, and Invasion by George F. Vande Woude and George Klein (Eds.)