Get Biocatalysis: Fundamentals and Applications PDF

By Andreas S. Bommarius, Bettina R. Riebel-Bommarius

ISBN-10: 3527303448

ISBN-13: 9783527303441

The full diversity of biocatalysis, from an organization grounding in theoretical suggestions to in-depth assurance of functional purposes and destiny views. The publication not just covers reactions, items and approaches with and from organic catalysts, but additionally the method of designing and bettering such biocatalysts.One specified characteristic is that the fields of chemistry, biology and bioengineering obtain equivalent awareness, hence addressing practitioners and scholars from all 3 components.

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Sample text

Where? What? , Germany “lock-and-key” concept (Nobel prize 1902) 1903 Henry D. Dakin London, UK 1st enantioselective synthesis, with oxynitrilase 1908 Otto Röhm Darmstadt, Germany Patent for enzymatic treatment of leather (with trypsin) 1913– 1915 Röhm Company Darmstadt, Germany 1st laundry detergent with enzyme (pancreatin): “Burnus” 1926 James B. , Ithaca, NY, USA 1st enzyme crystallized: urease from jack beans (Nobel prize 1946) 1936 Ernst Sym 1944 Linus Pauling Caltech, Pasadena, CA, USA 1st attempt to explain catalysis as transition-state complementarity 1950 Pehr Edman Univ.

L. Kenyon, J. A. Gerlt, G. A. Petsko, and J. W. Kozarich, Mandelate racemase: structure–function studies of a pseudosymmetric enzyme, Acc. Chem. Res. 1995, 28, 178–186. H. Kleinkauf and H. von Doehren, A nonribosomal system of peptide biosynthesis, Eur. J. Biochem. 1996, 236, 335–351. J. R. Knowles, Enzyme catalysis: not different, just better, Nature 1991, 350, 121−124. A. Liese and M. V. Filho, Production of fine chemicals using biocatalysis, Curr. Opin. Biotechnol. 1999, 10, 595–603. A. Liese, K.

I. Stirling, The use of aminotransferases for the production of chiral amino acids and amines, in Chirality in Industry, A. N. Collins, G. N. Sheldrake, and J. ), Wiley, New York, 1992, pp. 209–222. A. J. J. Straathof, S. Panke, and A. Schmid, The production of fine chemicals by biotransformations, Curr. Opin. Biotechnol. 2002, 13, 548–556. M. J. Taschner and D. J. Black, The enzymatic Baeyer–Villiger oxidation: enantioselective synthesis of lactones from mesomeric cyclohexanones, J. Am. Chem. Soc.

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Biocatalysis: Fundamentals and Applications by Andreas S. Bommarius, Bettina R. Riebel-Bommarius

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