Bruce C Baguley; David J Kerr's Anticancer drug development PDF

By Bruce C Baguley; David J Kerr

ISBN-10: 0120726513

ISBN-13: 9780120726516

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Shieh, S. , and Prives, C. (2000). The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14, 289–300. 30 POMMIER, YU, AND KOHN Shieh, S. , and Prives, C. (1997). DNA damageinduced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325–334. , and Terakawa, N. (2000). Mechanism of the combination effect of wild-type TP53 gene transfection and cisplatin treatment for ovarian cancer xenografts. Eur. J. Cancer 36, 1869–1875.

CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13, 1501–1512. Shieh, S. , and Prives, C. (2000). The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14, 289–300. 30 POMMIER, YU, AND KOHN Shieh, S. , and Prives, C. (1997). DNA damageinduced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325–334. , and Terakawa, N. (2000). Mechanism of the combination effect of wild-type TP53 gene transfection and cisplatin treatment for ovarian cancer xenografts.

Hannon, G. , and Beach, D. (1993). A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366, 704–707. Seynaeve, C. , Sausville, E. , and Worland, P. J. (1993). Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells. Cancer Res. 53, 2081–2086. , Kohn, K. , and Pommier, Y. (1997a). Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53.

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Anticancer drug development by Bruce C Baguley; David J Kerr


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